- Alex Straumann
- Ingrid Terreehorst
- The Netherlands
- Antonella Cianferoni
- Carina Venter
- United Kingdom
Last updated: 21 July 2017
- Alain Schoepfer
WG on Eosinophilic Esophagitis - About UsEosinophilic esophagitis (EoE) is a chronic, immune-mediated inflammatory condition of the esophagus. It may occur in all ages with characteristic symptoms of esophageal dysfunction, while diagnosis is confirmed by endoscopic findings and a significant esophageal eosinophilia.
In adults, it is associated with difficulty in swallowing, food impaction, chest pain and stricture formation in the esophagus. In children, symptoms include vomiting and regurgitation, feeding disorders and oral aversion, food impaction and a general failure to thrive. Endoscopic findings that might signal eosinophilic esophagitis include rings, stricture, furrow or straight lines, white spots, and a small-caliber esophagus. However, endoscopy in patients with EoE may result without pathological findings.
The etiology of EoE is not known, however atopy is a risk factor. Most patients with EoE are allergic to inhalants and food allergens. But in 30% of patients, endoscopic exams turn up normal.
Treatment of EoE is mainly based on dietary restrictions and antiinflamatory medications, while endoscopical interventions are necessary in severe cases of esophageal stenosis.
The EoE WG intents to inform and update EAACI members on this diseases, to offer educational tools and organize educational meetings on EoE.