Expert Meeting attempts to redefine IgE-associated allergies to improve our understanding of these complex diseases
EU project MeDALL continues to investigate the causes of allergies
Barcelona, June 29, 2011 - Allergic diseases are complex disorders: the interplay of genetic, environmental and socio-economic interactions determines disease expression. Different phenotypes thus frequently co-exist and there are many different definitions and classifications of allergic disease. For this reason, medical scientists come together in an expert meeting from June 29th to 30th 2011 in Barcelona, Spain with the goal of reaching a consensus on novel definitions of the different allergic diseases from birth to adolescence. These diseases include asthma, rhino-conjunctivitis, atopic eczema, food allergy and anaphylaxis. It follows the first MeDALL conference where current knowledge on IgE-mediated phenotypes was presented. The meeting is part of the EU-funded research project MeDALL, which investigates the causes of allergy.
Goal: To agree on the definition of the classical phenotypes for the MeDALL project
There is great variability in how to define the allergic diseases and how these definitions are used in clinical practice and research. Since MeDALL is a multidisciplinary project an agreement on the definitions of allergic phenotypes and standardization of its application to birth cohorts is needed. The meeting of experts in Barcelona will establish the MeDALL definitions of allergic phenotypes. The meeting agreements will be complemented by the results of a systematic review of the literature which is underway. These activities are part of Work Package 2 coordinated by Josep M Anto.
Jean Bousquet, MeDALL Project Coordinator and Chairman of the Scientific Seminar (Inserm and Montpellier University, France) says: “This expert meeting is an important step for structuring and standardising the current knowledge in the field of allergy. The MeDALL project will help us to improve our knowledge about allergic disorders and hopefully to confine the effects of this widespread disease.” MeDALL’s scientific coordinator Josep M Anto (CREAL, Barcelona, Spain) is convinced that “This meeting will be an important step towards achieving an evidence-based way of defining and classifying allergic diseases.”
MeDALL stands for “Mechanisms of the Development of ALLergy” and intends at improving the health of European citizens by using data gathered by previous birth cohort studies carried out across Europe. The MeDALL consortium encompasses 23 public and private institutions, including 3 European SMEs whose specific complementary scientific expertise will contribute to MeDALL objectives. The project is coordinated by the Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, France and the Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain. MeDALL has received funding from the European Union Seventh Framework Programme (FP7) under grant agreement n° 261357 and started in December 2010.
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