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Before proceeding to invasive laboratory tests, specific antibody levels were measured before and 4 weeks after immunization with 23-valent pneumococcal vaccine, which revealed poor response to polysaccharides antigens (Pre-immunisation: 0.5 µg/ml, Post-immunisation: 0.7µg/ml). She was diagnosed as having Specific Antibody Deficiency (SAD) and started on prophylactic antibiotic (Trimethoprime / Sulfamethoxazole 4 mg/kg/day).


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