Regional Adult Cystic Fibrosis Unit
St James’s Hospital
I studied medicine at the University of Leeds between 1995 and 2001. Following graduation I spent my early years as a doctor in both Leeds and Nottingham and developed a keen interest in Respiratory Medicine. In 2005 I started higher specialist training and it was during this time that I became very involved with Cystic Fibrosis.
What amazed me about patients with Cystic Fibrosis was the frequency of hypersensitivity reactions and how they had such a detrimental effect on patient’s outcomes. I was equally surprised by the lack of research in this area and it was at this point that my interest in drug hypersensitivity developed. Together with Professor Kevin Park and Dr Dean Naisbitt at the University of Liverpool we have been successful in characterising these reactions and understanding more about the mechanisms involved. We will shortly be starting a prospective study to investigate risk factors leading to the development of drug hypersensitivity. In addition we are investigating the immune responses during drug desensitization and I am a member of the ENDA Taskforce on Desensitization for Non-immediate Reactions.
Aside from drug hypersensitivity my interests are around respiratory infections and individual patient’s immune response to them. At present we are undertaking work exploring the impact of rhinovirus infections on the airway of patients with Cystic Fibrosis.
I regularly attend ENDA meetings and have received a lot of support and encouragement from other members. I have seen the positive impact that EAACI has, especially regarding education and guidelines. I am keen to be involved with this and help maintain this high standard.