Covering both clinical and transitional topics of a particular field, EAACI Master Classes aim to dive deeper and therefore target professionals and specialists with a higher level of experience. Conducted in intimate workshop formats of up to 60 international participants, they offer an excellent interactive platform for the exchange of knowledge over two days.
EAACI Master Class on Biologicals
Personalised Treatments of Chronic Inflammatory Upper and Lower Airways Disease:
Biologicals, Immunomodulators and Other Targeted Therapeutics
13 - 14 April 2018 Prague, The Czech Republic

Organised by:
Asthma Section, ENT Section, Basic & Clinical Immunology Section

MC Biologicals Prague

Educational Aims:
The increasing insight into the genetic, innate and adaptive mechanisms and their interaction with the environmental factors in asthma and allergic disease gives rise to targeted treatments. This master class will review and highlight important aspects and novel insights into the basic mechanisms and how they translate into the clinical presentation of (non) allergic asthma and rhinitis. In addition, novel targeted therapeutic options, including biologicals, anti-mediator drugs and immunomodulators, will be addressed while experience with these agents in clinical practice will be discussed in plenary sessions and workshops.

Expected Learning Outcomes:
We anticipate that the set up and the topics in this master class will broaden insights into the underlying mechanisms and the links to targeted therapeutic options for (non) allergic asthma and upper airway disease. The international exchange of clinical experience with these novel agents and discussions on potential future applications should create a platform to define unmet (research) needs.

So, attending this master class the participants will receive updates and gain insight into:
  • innate and adaptive basic mechanisms in asthma and rhinitis
  • the role of microbioma within upper and lower airways
  • the role of biomarkers, phenotypes, and endotypes in precision medicine of asthma and rhinitis available biologicals and their effectiveness in the treatment of asthma and rhinitis (which patients benefit from what biologicals?)
  • the role of allergen immunotherapy in the treatment of allergic asthma and rhinitis
  • potential novel therapeutic targets in asthma and rhinitis
  • how to apply targeted therapy in asthma and rhinitis through case reports and interactive sessions with experts

Target Audience:
Whereas EAACI’s allergy schools are tailored for more junior attendees, master classes require a higher level of professional experience and offer an excellent platform for the exchange of knowledge. However, age is not a criterion for exclusion.
This master class is intended for clinicians, researchers and lab specialists who want to learn more about Treatments of Chronic Inflammatory Upper and Lower Airways Disease, focusing on Asthma and Rhinitis.

CME Accreditation:
An application will be made to the UEMS-EACCME® for CME accreditation of this meeting. Further information will be available at a later stage.
For more information regarding CME accreditation, please click here.

Submission of Case Reports:
This master class will include interactive case reports and plenary discussion sessions in which case reports submitted by attendees will be discussed. Case reports can now be submitted by email to This email address is being protected from spambots. You need JavaScript enabled to view it.
Furthermore, the cases can be presented with or without slides and will be discussed with faculty and attendees.



The master class will be held over two days and will include lectures, workshops, practical discussions, and case presentations.

Topics covered:
  • Innate and adaptive Immunity in Rhinitis and Asthma
  • The Role of Microbiome in Upper & Lower Airways and the Effect of Treatment
  • Mechanisms driving Corticosteroid Insensitivity
  • Endotype-driven Treatment – a Step towards Precision Medicine in Asthma
  • Anti-mediator Approaches for Asthma
  • Role of Biologicals in Asthma Comorbidities
  • New Therapeutic Targets: where do we stand? (Includes anti-IL25/anti-IL-33/anti-TSLP; PI3K inhibitors/antibiotics)
  • Which phenotypes benefit from SCIT; which from SLIT?
  • Which phenotypes benefit from anti-IgE and which type of anti-IgE treatment?
  • Which phenotypes benefit from anti-IL-5, anti-IL-4 and/or anti-IL-13)-directed approaches?
  • Uncontrolled allergic and non-allergic Rhinitis (Includes diagnosis/ Biomarkers; dysfunctional barrier; treatment options e.g. IT, Biologicals, other)
  • Recalcitrant Chronic Rhinosinusitis (Includes diagnosis/Biomarkers; IT, Biologicals, other)
  • Endotype-driven Treatment of Chronic Rhinosinusitis with Nasal Polyps (Includes Diagnosis/Biomarkers, Biologicals, Antibiotics, other)

The master class will take place at the Lindner Hotel Prague Castle at one of the most beautiful locations in Prague.
Lindner Hotel Prague Castle
Strahovska 128
118 00 Prague
Czech Republic

If you wish to accommodate at the Lindner Hotel Prague Castle for a price of EUR 125 (price per room including breakfast, single occupancy, per night) please fill this form, and send it directly to the hotel at the address provided in the form.

Please note that EAACI cannot be held responsible for any accommodation request/refund.

Online registration will be available until the maximum capacity of 50 participants is reached.


Registration Fees:
Early bird registration fees until 2 February 2018:
EAACI Member* / EAACI Junior Member EUR 500.00
Non-Member EUR 800.00

Registration fee after 2 February 2018:
EAACI Member* / EAACI Junior Member EUR 600.00
Non-Member EUR 900.00

*Only EAACI Members who have paid the full amount of their membership fee are entitled to this reduced fee. Please make sure to pay the EAACI membership before you register for this Master Class.

Registration for the Master Class includes:
  • Coffee breaks (morning and afternoon)
  • Lunch on Friday and Saturday
  • Welcome dinner on Friday

The registration fee does not include travel costs and accommodation.

We are looking forward to seeing you in Prague.

Organising Committee

Zuzana Diamant
Local Organising Chair

Oscar Palomares Gracia
Local Organising Secretary

Philippe Gevaert
ENT Section Chair

Martina Vasakova
Asthma Section Board Member

For more information, please contact:
EAACI Headquarters
Hagenholzstrasse 111
3rd Floor
8050 Zurich
Tel: +41 44 205 55 33

Scientific aspects: This email address is being protected from spambots. You need JavaScript enabled to view it.
Logistical aspects: This email address is being protected from spambots. You need JavaScript enabled to view it.

Potential Conflict of Interest Declaration
The European Academy of Allergy and Clinical Immunology (EAACI) takes pride in offering scientific educational events of the highest standard. In accordance with UEMS criteria EAACI dutifully request all committee and faculty members to declare any interests they may have which could influence, or might be perceived to influence their judgement or behaviour.

Please click on the following links to view the respective Conflict of Interest forms.
- Committee
- Faculty
Last updated 19 January 2018